Puncture Testing of Pharmaceutical Bottle Seals

Basma
Biyomedikal
Biyomedikal/Medikal/Sağlık Hizmeti

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The Food and Drug Administration requires that many consumer goods, such as some over-the-counter pharmaceutical bottles, be sealed to protect drugs from bacteria, light, liquids, etc. This seal needs to be strong enough to protect the drug from harmful elements, but also needs to be easy to remove by the consumer. Many bottle seals contain a plastic or foil film over the opening that requires the consumer to puncture it with his or her finger. The force required to puncture the seal can be simulated with a compression test on an Instron Universal Testing System.

We used a 3345 frame with a 50 N load cell to perform puncture tests on bottle seals. The bottle can sit on a lower platen, with a rounded, or ball-end probe attached to the load cell. The rounded probe best simulates a human finger. The test was ran at 200 mm/min until the seal was penetrated completely. We recommend using Bluehill 3 Software for this application to collect graphical data and perform calculations such as maximum load or extension.

Bluehill Software

Webinar on Bluehill Software presented by Jim Ritchey and Frank Lio on July 15, 2004, October 27, 2004 and December 8, 2004.

Ürünler
2/9/2006
11.1 KB

2501 Series Compression Platens

Ürünler
8/19/2008
108.6 KB

3300 Series Single Column Models

The 3300 single column models have been developed to address the requirements of standardized and routine testing. These models provide the user with Instron quality at the most affordable price. Load capacity from 0.5 kN to 5 kN with a maximum speed of 1000 mm/min. These systems conform to all relevant European standards and carry a CE mark.

Ürünler
3/2/2010
507.6 KB

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Puncture Testing of Pharmaceutical Bottle Seals

Bluehill Software

2501 Series Compression Platens

3300 Series Single Column Models

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